Definition
MOTS-c (mitochondrial open reading frame of the 12S rRNA type-c) is a mitochondrial-derived peptide, CAS 1627580-64-6, commonly cited sequence MRWQEMGYIFYPRKLR.
Published work explores metabolic signaling models. Research reagents are not for human use.
Key Facts
- Compound: MOTS-c
- CAS: 1627580-64-6
- Length: 16 amino acids
- Sizes: 10 mg, 40 mg
- Use: Laboratory research only
Last reviewed: 2026-10-15
Key Characteristics
MOLECULAR PROFILE
Sequence: MRWQEMGYIFYPRKLR
CAS: 1627580-64-6
Length: 16 aa
PHYSICAL PROPERTIES
Form: White to off-white lyophilized powder
Solubility: Soluble in bacteriostatic water or sterile lab-grade water
Stability: Stable when stored dry, cold, and protected from light
Storage: -20°C preferred (lyophilized); 2-8°C after reconstitution
Mechanism of Action (Research Context)
MOTS-c is investigated for roles in cellular energy sensing and stress-response pathways in experimental systems. Findings do not authorize human administration of research chemicals.
Research Applications
- Metabolic signaling assays
- Mitochondrial peptide biology
- In-vitro stress/energy pathway experiments
Laboratory Notes
High-level handling notes for MOTS-c. Detailed reconstitution steps live on the product page. Always defer to your lab SOP and batch COA.
Scientific References
- Lee C, et al. MOTS-c and metabolic homeostasis. Cell Metab. 2015.
- PubChem / literature for CAS 1627580-64-6.
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Legal Disclaimer
Content is for scientific orientation. Materials from Osae Research are for laboratory research only. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.